Antimicrobial Activity and Characterization of an Alkaloid as a Natural Ligand and Its Co (II) Complex
نویسنده
چکیده
Metal to ligand complex with molecular formula [Co (L)]Cl2 , (L= thebaine) of thebaine as an alkaloid and its cobalt complex have been prepared and characterized by elemental analysis, 1H-NMR, IR and UV-Visible spectroscopy. The Biological activity of alkaloids is believed to increase when they are coordinated with transition metal ions. However, the literature on this subject is contradictory and the outcome seems to largely depend on the experimental conditions. The results of this analyze indicate that the complex has a Co (II) ion coordinated via positions 4, 5epoxy (oxygen atom) and 6 of the thebaine. The antimicrobial activity of this complex was studied and the thebaine –Co (II) complex 1 showed antibacterial activities.
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